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Biomarkers available since age 53. Biomarkers highlighted in bold are not present in other UK birth cohorts | |||
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System | Biomarkers at 53 years | Biomarkers at 60-64 years | Biomarkers at 68-70 years |
Metabolic | Adiponectin (μg/mL) | ||
Cholesterol, Total (mmol/L) | Cholesterol, Total (mmol/L) | Cholesterol, Total (mmol/L) | |
Cholesterol, High density Lipoprotein, LDL (mmol/L) | Cholesterol, High density Lipoprotein, HDL (mmol/L) | Cholesterol, High density Lipoprotein, HDL (mmol/L) | |
Cholesterol, Low density Lipoprotein, LDL (mmol/L) | Cholesterol, Low density Lipoprotein, LDL (mmol/L) | Cholesterol, Low density Lipoprotein, LDL (mmol/L) | |
Triglycerides (mmol/L) | Triglycerides (mmol/L) | Triglycerides (mmol/L) | |
Glucose (nmol/L) | |||
Insulin (pmol/L) | |||
Leptin (ng/mL) | |||
Lipoprotein[a] (mg/dL) | |||
Proinsulin (pmol/L) | |||
Glycated Haemoglobin, HbA1c (mmol/mol) | Glycated Haemoglobin, HbA1c (mmol/mol) | Glycated Haemoglobin, HbA1c (mmol/mol) | |
Diet & Iron Markers | Ferritin (ng/mL) | ||
Haemoglobin, Hb (g/L) | Haemoglobin, Hb (g/L) | ||
Iron (μg/dL) | |||
Vitamin C (μmol/L) | |||
Vitamin D3 (250HD3) (ng/mL)† | |||
Inflammatory | Anti-Thyroperoxidase, TPO (IU/mL) | ||
Basophils (x109/L) | Basophils (x109/L) | ||
C-Reactive Protein, CRP (mg/L) | |||
Eosinophils (x109/L) | Eosinophils (x109/L) | ||
Fibrinogen (g/L) | |||
Homocysteine concentration (μmol/L) | |||
Interleukin-6, IL-6 (pg/mL) | |||
Tissue Plasminogen Activator, TPA (ng/mL) | |||
Von Willebrand Factor, VWF (IU/dL) | |||
Red Cell Folate, RCF (nmol/L) | |||
Lymphocytes (x109/L) | Lymphocytes (x109/L) | ||
Mean Corpuscular Volume, MCV | |||
Mean Corpuscular Haemoglobin, MCH | |||
Mean Platelet Volume, MPV | |||
Monocytes (x109/L) | Monocytes (x109/L) | ||
Neutrophils (x109/L) | Neutrophils (x109/L) | ||
Platelet count (x109/L) | Platelet count (x109/L) | ||
Platelet Distribution Width, PDW (%) | |||
Potassium (mmol/L) | |||
Protein (blood), Total (g/L) | |||
Red Blood Cell, RBC, count (x1012/L) | Red Blood Cell, RBC, count (x1012/L) | ||
White Blood Cell, WBC, count (x109/L) | White Blood Cell, WBC, count (x109/L) | ||
Neuro-Endocrine | Cortisol (saliva) (nmol/L) | ||
DHEAS (umol/L) | DHEAS (umol/L) | ||
Insulin Growth Factor 1, IGF-1 (nmol/L) | Insulin Growth Factor 1, IGF-1 (nmol/L) | ||
Insulin Growth Factor 2, IGF-2 (nmol/L) | |||
Insulin Growth Factor IGF-BP3 (ng/mL) | |||
Sex hormone binding globulin, SHBG (nmol/L) | Sex hormone binding globulin, SHBG (nmol/L) | ||
Testosterone (nmol/L) | Testosterone (nmol/L) | ||
Thyroid tests (T3, T4) (pmol/L) | |||
Thyroid Stimulating Hormone, TSH (mU/L) | |||
Kidney & Liver | Calcium (mmol/L) | ||
Creatinine (blood, urine) (mmol/L) | |||
Phosphate (mmol/L) | |||
Urea (nmol/L) | |||
Alanine Transaminase , ALT (IU/L) | |||
Alkaline Phosphatase, ALP (IU/L) | |||
Aspartate Transaminase, AST (IU/L) | |||
Albumin (blood, urine) (mg/L) | |||
Bilirubin (mg/dL) | |||
Cystatin C (mg/L) | |||
Gamma Glutamyl Transferase, GGT (IU/L) | |||
Glucose (urine) (dipstick) (mmol/L) | |||
Globulin (mg/dL) | |||
Ketones (urine) (dipstick) (positive/negative) | |||
Liver Iron Concentration, LIC (%) | |||
Potassium (serum) (mmol/L) | |||
Potassium (urine) (mmol/L) | |||
Protein (urine) (positive/negative) | |||
Sodium (urine) (mmol/L) | |||
Sodium (blood) (mmol/L) | |||
Urate (g/L) |